Concepedia

The HdhQ150/Q150 knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes

Ben Woodman, Rachel Butler, Christian Landles, Michelle K. Lupton, Jamie Tse, Emma Hockly, Hilary Moffitt, Kirupa Sathasivam, Gillian P. Bates

Brain Research Bulletin · 2006 · 166 citations · 60 references

DOI

Concepts

References

60

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

, , +16

Manipulating the mouse embryo: A laboratory manual

Martin Johnson · Trends in Genetics · 1986 · 2.3K citations

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Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

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Characterization of Progressive Motor Deficits in Mice Transgenic for the Human Huntington’s Disease Mutation

Rebecca J. Carter, Lisa A. Lione, Trevor Humby et al. · Journal of Neuroscience · 1999 · 959 citations · Full text

, , +17