Concepedia

STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis

Udo Holtick, Martina Vockerodt, Diana Pinkert, Nils Schoof, Benjamin Stürzenhofecker, N Kussebi, Kirsten Lauber, Sebastian Wesselborg, Dennis Löffler, Friedemann Horn,

Leukemia · 2005 · 94 citations · 34 references

DOI

Concepts

References

34

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.7K citations · Full text

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Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

Naftaly Meydan, T Grunberger, Harjit Dadi et al. · Nature · 1996 · 912 citations

, , +9

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

Ralf C. Bargou, Florian Emmerich, Daniel Krappmann et al. · Journal of Clinical Investigation · 1997 · 765 citations · Full text

, , +15

Stat proteins and oncogenesis

Jacqueline Bromberg · Journal of Clinical Investigation · 2002 · 678 citations

, , +14

Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells

Alok C. Bharti, Nicholas J. Donato, Bharat B. Aggarwal · The Journal of Immunology · 2003 · 504 citations · Full text

, , +13