Journal of neurosurgery · 1981 · 105 citations · 26 references
MedicineCardiologyPulmonologyUltrasonographyUltrasoundCardiac UltrasonographyCardiac UltrasoundCardiovascular MonitoringDoppler UltrasonographyDoppler UltrasoundHemodynamicsAuscultation Of Heart SoundsBlood PressureDoppler MeasurementsElectrocardiographic ChangesVenous Doppler EvaluationVenous Ultrasound
Venous air embolism can usually be detected by the use of a precordial Doppler ultrasound monitor at an air infusion rate as low as 0.015 ml/kg/min, and consistently at a rate of 0.021 ml/kg/min. This is in contrast to previously reported thresholds wherein the first physiological change, a gasp, occurs at 0.36 ml/kg/min, electrocardiographic changes first take place at 0.60 ml/kg/min, drop in blood pressure at 0.69 ml/kg/min, increased central venous pressure at 0.40 ml/kg/min, and end-tidal CO2 decreases at 0.42 ml/kg/min. The first change in heart sounds monitored through an esophageal stethoscope is not detectable until an air infusion rate of 1.70 ml/kg/min, and the classical mill-wheel murmur does not occur until 1.96 ml/kg/min. This demonstrates that Doppler ultrasound can detect venous air embolism before the earliest physiological changes, in contrast to most other methods which do not detect venous air embolism until after cardiopulmonary changes have become well established.
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Pulmonary (venous) air embolism
Thomas M. Durant, Joan H. Long, Morton J. Oppenheimer · American Heart Journal · 1947 · 307 citations
Pathophysiology of Intravenous Air Embolism in Dogs
D.C. Adornato, Philip L. Gildenberg, Carlos M. Ferrario et al. · Anesthesiology · 1978 · 214 citations · Full text
J. G. B. Russell, Carole Pritchard · The Lancet · 1975 · 132 citations