Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.3K citations

Life Sciences, Biochemistry, Molecular Biology +12

Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers

Frank H. Gawin · Archives of General Psychiatry · 1986 · 1.2K citations

Nursing, Psychiatry, Psychology +16

Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point

Serge H. Ahmed, George F. Koob · Science · 1998 · 1.2K citations

Nursing, Behavioral Sciences, Psychology +17

Reinstatement of cocaine-reinforced responding in the rat

Harriet de Wit, Jane Stewart · Psychopharmacology · 1981 · 946 citations

Life Sciences, Behavioral Sciences, Psychology +11

Decreased dopamine D₂ receptor availability is associated with reduced frontal metabolism in cocaine abusers

Nora D. Volkow, Joanna S. Fowler, G.‐J. Wang et al. · Synapse · 1993 · 920 citations

Medicine, Neuroscience, Psychiatry +17