Tetravalent dengue DIIIC protein together with alum and ODN elicits a Th1 response and neutralizing antibodies in mice

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

Mirjam Kool, Thomas Soullié, Menno van Nimwegen et al. · The Journal of Experimental Medicine · 2008 · 983 citations · Full text

Life Sciences, Immunology, Adaptive Immunity +16

Programming the magnitude and persistence of antibody responses with innate immunity

Sudhir Pai Kasturi, Ioanna Skountzou, Randy A. Albrecht et al. · Nature · 2011 · 974 citations · Full text

Life Sciences, Immunology, Cellular Immunology +13

Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial

Maria Rosario Capeding, Ngoc Huu Tran, Sri Rezeki Hadinegoro et al. · The Lancet · 2014 · 969 citations

Veterinary Medicine, Infectious Diseases, Pediatrics +17

Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

Arunee Sabchareon, Derek Wallace, Chukiat Sirivichayakul et al. · The Lancet · 2012 · 814 citations

Veterinary Medicine, Child Health, Infectious Diseases +17

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

Martina Beltramello, Katherine L. Williams, Cameron P. Simmons et al. · Cell Host & Microbe · 2010 · 597 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16