[Purification and study of bronchogenic cysts mucins (author's transl)].

Abstract

Abstract Glycoproteins rich in fucose, or N -acetylneuraminic acid or sulfate groups were isolated form three bronchogenic cysts. The polypeptide backbone of these molecules was rich in hydroxyaminoacids (25–40%) and devoid of cystein. Arginine was the only n-terminal group detectable. The carbohydrate-peptide linkages of the different species of glycoproteins were studied and were alkali-labile. Sulfate-rich glycoproteins had a lower ratio Thr/Ser, fewer carbohydrate-peptide linkages, longer carbohydrate chains and higher amounts of arginine. The linkages seem to involve mainly serine. The ratios Thr/Ser and Pro/Gly were similar.