Receptor-mediated transcytosis: A mechanism for active extravascular transport of nanoparticles in solid tumors

Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein

Michael M. Ollmann, Brent D. Wilson, Yingkui Yang et al. · Science · 1997 · 1.9K citations

Life Sciences, Endocrinology, Molecular Biology +14

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

Dmitri B. Kirpotin, Daryl C. Drummond, Yi Shao et al. · Cancer Research · 2006 · 1.1K citations · Full text

Pharmacy, Cancer Biology, Molecular Pharmaceutics +17

Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality <i>in vivo</i> imaging

Derek W. Bartlett, Helen C. Su, Isabel J. Hildebrandt et al. · Proceedings of the National Academy of Sciences · 2007 · 797 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice.

John R. Shutter, Melissa Graham, Alfred C. Kinsey et al. · Genes & Development · 1997 · 671 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +11

4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity.

Tomi K. Sawyer, Pauline J. Sanfilippo, Victor J. Hruby et al. · Proceedings of the National Academy of Sciences · 1980 · 578 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17