Concepedia

Mis3 with a conserved RNA binding motif is essential for ribosome biogenesis and implicated in the start of cell growth and S phase checkpoint

Hiroshi Kondoh, Tatsuro Yuasa, Mitsuhiro Yanagida

Genes to Cells · 2000 · 15 citations · 66 references

DOIFull text

Open access

Abstract

Mis3 is essential for ribosome biogenesis, supports S phase checkpoint, and is needed for the coupling between growth and cell cycle. Whether Mis3 interacts solely with ribosomal precursor RNA remains to be determined.

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