Behavioral evidence for a modulating role of σ ligands in memory processes. I. Attenuation of dizocilpine (MK-801)-induced amnesia

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Richard Morris, Eric Anderson, Gary Lynch et al. · Nature · 1986 · 3.6K citations

Life Sciences, Neuroscience, Pharmacology +15

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

W R Martin, C. G. Eades, JP Thompson et al. · Journal of Pharmacology and Experimental Therapeutics · 1976 · 3K citations

Medicine, Pharmacology, Veterinary Pharmacology +16

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

G.L. Collingridge, Steven J. Kehl, H. McLennan · The Journal of Physiology · 1983 · 2.4K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

Nabil A. Anis, Stephen C. Berry, N.R. Burton et al. · British Journal of Pharmacology · 1983 · 1.4K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

A proposal for the classification of sigma binding sites

Rémi Quirion, Wayne D. Bowen, Yossef Itzhak et al. · Trends in Pharmacological Sciences · 1992 · 754 citations

Pharmacy, Molecular Biology, Molecular Recognition +7