FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

René H. Medema, Geert J.P.L. Kops, Johannes L. Bos et al. · Nature · 2000 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +14

Mesenchyme Forkhead 1 ( <i>FOXC2</i> ) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

Sendurai A. Mani, Jing Yang, Mary W. Brooks et al. · Proceedings of the National Academy of Sciences · 2007 · 579 citations · Full text

Medicine, Molecular Biology, Oncology +15

TNM residual tumor classification revisited

Christian Wittekind, Carolyn C. Compton, Frederick L. Greene et al. · Cancer · 2002 · 491 citations

Medicine, Oncology, Surgery +15

The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

Li-Bing Song, Jun Li, Wenting Liao et al. · Journal of Clinical Investigation · 2009 · 396 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

Sanjit K. Roy, Rakesh K. Srivastava, Sharmila Shankar · Journal of Molecular Signaling · 2010 · 376 citations · Full text

Life Sciences, Cell Biology, Oncology +17