Identification of ClC-2 and CIC-K2 Chloride Channels in Cultured Rat Type IV Spiral Ligament Fibrocytes

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

Lutz Nährlich, Jochen G. Mainz, Constantin Adams et al. · Cellular Physiology and Biochemistry · 2013 · 2.5K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III

David B. Simon, Ranjit S. Bindra, Traci A. Mansfield et al. · Nature Genetics · 1997 · 870 citations

Life Sciences, Genetics, Molecular Genetics +13

A chloride channel widely expressed in epithelial and non-epithelial cells

Astrid Thiemann, Stefan Gründer, Michael Pusch et al. · Nature · 1992 · 611 citations

Life Sciences, Cell Biology, Physiology +14

Barttin is a Cl- channel β-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion

Raúl Estévez, Thomas Boettger, Valentin Stein et al. · Nature · 2001 · 571 citations

Life Sciences, Nephrology, Physiology +15