Transforming Growth Factor-β Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers - Concepedia

Concepedia

Publication | Open Access

Transforming Growth Factor-β Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers

DOI Full Paper Access

82

Citations

40

References

2008

Year

Africa F. Wallace, Veena Kapoor, Jing Sun, Paul Mrass, Wolfgang Weninger, Daniel F. Heitjan, Carl H. June, Larry R. Kaiser, Leona Ling, Steven Μ. Albelda

Clinical Cancer Research

Abstract

We found that systemic blockade of TGF-beta receptor activity augmented the antitumor activity of adoptively transferred T cells and may thus be a useful adjunct in future clinical trials.

References

	Year	Citations

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