Concepedia

Characterisation and identification of the human N+-glucuronide metabolite of cediranib

Eva M. Lenz, Michael L. Spear, Christopher R. Drake, Chris R. J. Pollard, Michelle M. Ward, Timothy Schulz-Utermoehl, M. P. Harrison

Journal of Pharmaceutical and Biomedical Analysis · 2010 · 13 citations · 17 references

DOI

Concepts

References

17

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

K. Jin Kim, Bing Li, Jane Winer et al. · Nature · 1993 · 3.6K citations

, , +14

AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients

Tracy T. Batchelor, A. Gregory Sorensen, Emmanuelle di Tomaso et al. · Cancer Cell · 2007 · 1.8K citations · Full text

, , +17

AZD2171: A Highly Potent, Orally Bioavailable, Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitor for the Treatment of Cancer

Stephen R. Wedge, Jane Kendrew, Laurent Hennequin et al. · Cancer Research · 2005 · 711 citations · Full text

, , +17

Phase I Clinical Study of AZD2171, an Oral Vascular Endothelial Growth Factor Signaling Inhibitor, in Patients With Advanced Solid Tumors

Joachim Drevs, Patrizia Siegert, Michael Medinger et al. · Journal of Clinical Oncology · 2007 · 302 citations

, , +17

Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins.

Mitchell D. Green, Thomas R. Tephly · PubMed · 1998 · 134 citations

, , +9