MedicinePharmacologyPsychiatryNeuropharmacologyPsychopharmacologyPsychophysiologyCentral Nervous System Drug ActionsSerotonergic PharmacologySerotonergic SignalingCentral Nervous System DepressantsHydroxyzine TherapyPharmacodynamics Of Psychoactive SubstancesPharmacology Of Serotonergic Agents
THIS STUDY was designed to investigate the effects of a psychoactive drug, hydroxyzine, on information processing capability and levels of Central Nervous System (CNS) activation of psychiatric patients undergoing physical and cognitive stress. It has been shown by a number of investigators that, in addition to being a Psychotropic agent, hydroxyzine has been useful as an analgesic,<sup>1</sup>as well as in alcoholism,<sup>2</sup>obstetrics,<sup>3,4</sup>treatment of allergies,<sup>5</sup>oral surgery,<sub>6</sub>reducing tension in children,<sup>7</sup>and senile patients.<sub>8</sub>It was also found to be an effective serotonin antagonist,<sup>9</sup>and to have anticholinergic and antihistaminic properties.<sup>1</sup>Electrophysiological studies reveal that conduction in frogs' sciatic nerves was blocked and muscle responses were progressively decreased and eventually completely disappeared with the administration of hydroxyzine.<sup>10</sup>In relation to the learning process, there is evidence that hydroyzine was effective in suppressing
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Electrical properties of the skin
Robert Edelberg · Medical Entomology and Zoology · 1967 · 214 citations
Natural Sciences, Electrical Engineering, Materials Science +12