Concepedia

Hydroxyzine Therapy

Hydroxyzine Therapy is a pharmacotherapeutic intervention within the class of anxiolytic therapies that utilizes the first-generation antihistamine hydroxyzine to exert anxiolytic effects through its antagonism of histaminergic and serotonergic receptors, distinguishing it from benzodiazepine- and SSRI-based treatments by its non-sedating (at therapeutic doses), non-habit-forming mechanism and rapid onset of action.

227

Publications

8.7K

Citations

837

Authors

283

Institutions

Publications per year

2017–2026

10

Parents

Publications

227

A Pilot Clinical Trial of Oral Pentosan Polysulfate And Oral Hydroxyzine in Patients With Interstitial Cystitis

Grannum R. Sant, Kathleen J. Propert, Philip M. Hanno et al. · The Journal of Urology · 2003 · 279 citations

, , +8

Efficacy and Safety of Hydroxyzine in the Treatment of Generalized Anxiety Disorder

Pierre‐Michel Llorca, C. Spadone, Olivier Sol et al. · The Journal of Clinical Psychiatry · 2002 · 142 citations

, , +17

Hydroxyzine therapy for interstitial cystitis

Theoharis C. Theoharides, Grannum R. Sant · Urology · 1997 · 142 citations

, , +3

Central Effects of Fexofenadine and Cetirizine: Measurement of Psychomotor Performance, Subjective Sleepiness, and Brain Histamine H<sub>1</sub>‐Receptor Occupancy Using <sup>11</sup>C‐Doxepin Positron Emission Tomography

Manabu Tashiro, Yumiko Sakurada, Kentaro Iwabuchi et al. · The Journal of Clinical Pharmacology · 2004 · 136 citations

, , +13

Pre-operative anxiolysis in children through a combined pharmacological therapy with hydroxyzine and a non-pharmacological distraction technique with a clown (SONRISA): study protocol for randomised double-blind clinical trial

Amanda López Picado, Belén Joyanes Abancens, Marina Laura Rodríguez Rojo et al. · Trials · 2020 · 136 citations · Full text

, , +17

1–5 of 227

Authors

837

  1. KJ
    Keith J. Simons

    University of Manitoba, Canada

    8 publications · 405 citations

    8

    h-index

  2. FE
    F. Estelle R. Simons

    University of Manitoba, Canada

    7 publications · 355 citations

    7

    h-index

  3. TC
    Theoharis C. Theoharides

    Tufts University, United States

    6 publications · 662 citations

    6

    h-index

  4. CG
    Consuelo García‐Gea

    Hospital de Sant Pau, Spain

    4 publications · 184 citations

    4

    h-index

  5. MT
    Manabu Tashiro

    Tohoku University, Japan

    3 publications · 237 citations

    3

    h-index

1–5 of 837

Institutions

283

  1. University of Manitoba

    Winnipeg, Canada

    8 h-index

    24 publications

    1.1K citations

  2. Tufts University

    Medford, United States

    6 h-index

    9 publications

    679 citations

  3. Tufts Medical Center

    Boston, United States

    5 h-index

    9 publications

    650 citations

  4. Sorbonne Université

    Paris, France

    5 h-index

    7 publications

    143 citations

  5. Hospital de Sant Pau

    Barcelona, Spain

    5 h-index

    15 publications

    611 citations

  6. Johns Hopkins University

    Baltimore, United States

    4 h-index

    5 publications

    295 citations

  7. UCB Pharma (Belgium)

    Brussels, Belgium

    4 h-index

    12 publications

    421 citations

  8. Northwestern University

    Evanston, United States

    4 h-index

    11 publications

    378 citations

1–8 of 283

Venues

  1. PubMed

    Repository · 54 publications · 1.6K citations

    23

    h-index

  2. Journal of Allergy and Clinical Immunology

    11 publications · 597 citations

    11

    h-index

  3. 8

    h-index

  4. Anesthesia & Analgesia

    7 publications · 180 citations

    7

    h-index

  5. JAMA

    5 publications · 248 citations

    5

    h-index

1–5