A proposed mechanism for chlorpromazine jaundice — defective hepatic sulphoxidation combined with rapid hydroxylation

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

A. Mahgoub, L. G. Dring, Jeffrey R. Idle et al. · The Lancet · 1977 · 1.2K citations

Pharmacy, Biochemistry, Pharmacology +6

Advances in biochemical psychopharmacology

M. H. Aprison · Neuropharmacology · 1970 · 1.2K citations

Medicine, Medicinal Chemistry, Pharmacology +6

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

David A. Evans, A. Mahgoub, T.P. Sloan et al. · Journal of Medical Genetics · 1980 · 540 citations · Full text

Life Sciences, Genetics, Pharmacology +17

Diseases of the Liver and Biliary System.

Annals of Internal Medicine · 1976 · 170 citations

Medicine, Internal Medicine, Pathology +12

Hepatic injury associated with the phenothiazines. Clinicopathologic and follow-up study of 36 patients.

K G Ishak, Nelson S. Irey · PubMed · 1972 · 109 citations

Pharmacy, Pharmacology, Pharmacotherapy +11