Synthesis of [2‐¹³C, 4‐¹³C]‐(2<i>R</i>,3<i>S</i>)‐catechin and [2‐¹³C, 4‐¹³C]‐(2<i>R</i>,3<i>R</i>)‐epicatechin

Abstract

Abstract The first synthesis of doubly labeled, [2‐ 13 C, 4‐ 13 C]‐(2 R ,3 S )‐catechin 15 and [2‐ 13 C, 4‐ 13 C]‐( 2R ,3 R )‐epicatechin 18 starting from labeled 2‐hydroxy‐4, 6‐bis(benzyloxy)acetophenone 3 and labeled 3, 4‐bis(benzyloxy)‐benzaldehyde 7 are described. Copyright © 2010 John Wiley &amp; Sons, Ltd.