Global changes in DNA methylation in Alzheimer’s disease peripheral blood mononuclear cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.3K citations

Life Sciences, Biochemistry, Molecular Biology +12

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8

The single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction: twenty-something years on

Piotr Chomczyński, Nicoletta Sacchi · Nature Protocols · 2006 · 2.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

Steen K.T. Ooi, Chen Qiu, Emily Bernstein et al. · Nature · 2007 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +15