Cadmium-Induced Nephropathy in Rats Is Mediated by Expression of Senescence-Associated Beta-Galactosidase and Accumulation of Mitochondrial DNA Deletion

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

Education, Cell Biology, Molecular Biology +15

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

Marisol Corral‐Debrinski, Terzah M. Horton, Marie T. Lott et al. · Nature Genetics · 1992 · 886 citations

Life Sciences, Genetics, Neuroscience +16

Detection of a specific mitochondrial DNA deletion in tissues of older humans

Gino Cortopassi, Norman Arnheim · Nucleic Acids Research · 1990 · 792 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +7

Multiple mitochondrial DNA deletions in an elderly human individual

Chunfang Zhang, Alessandra Baumer, Ronald J. Maxwell et al. · FEBS Letters · 1992 · 217 citations

Life Sciences, Genetics, Molecular Genetics +15

Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia

James J. Choi, Igor Shendrik, Monica Peacocke et al. · Urology · 2000 · 168 citations

Medicine, Cell Biology, Urology +17