Concepedia

Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases

John Stover, Oliver Kempski

Neuroscience Letters · 1997 · 110 citations · 18 references

DOI

Concepts

References

18

Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced

Antonello Novelli, Joseph Reilly, Paul G. Lysko et al. · Brain Research · 1988 · 977 citations

, , +14

Identification of Hypoxanthine Transport and Xanthine Oxidase Activity in Brain Capillaries

A. Lorris Betz · Journal of Neurochemistry · 1985 · 236 citations · Full text

, , +11

Oxygen free radicals regulate NMDA receptor function via a redox modulatory site

Elias Aizenman, Karen A. Hartnett, Ian J. Reynoldst · Neuron · 1990 · 205 citations

, , +15

Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms.

Andrea Volterra, Davide Trotti, Giorgio Racagni · Molecular Pharmacology · 1994 · 176 citations

, , +17

Neurotransmitters in cerebrospinal fluid reflect pathological activity

John Stover, Ulrike E. Pleines, Maria Cristina Morganti-Kossmann et al. · European Journal of Clinical Investigation · 1997 · 168 citations

, , +17