Concepedia

Synaptic Excitotoxicity

Synaptic Excitotoxicity is a pathological process in which excessive activation of synaptic glutamate receptors leads to disruptive ion fluxes and neuronal damage, distinguishing it from physiological excitatory synaptic transmission by its association with neurodegenerative mechanisms.

819

Publications

61.8K

Citations

3.4K

Authors

932

Institutions

Publications per year

2017–2026

98

Parents

Publications

819

Glutamate neurotoxicity and diseases of the nervous system

Dennis W. Choi · Neuron · 1988 · 8K citations

, , +14

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

Timothy H. Murphy, Masaomi Miyamoto, Antonio Sastre et al. · Neuron · 1989 · 1K citations

, , +17

Glutamate neurotoxicity in cortical cell culture is calcium dependent

Dennis W. Choi · Neuroscience Letters · 1985 · 815 citations

, , +16

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

TG Hastings · Journal of Neuroscience · 1995 · 781 citations · Full text

, , +17

Kainic acid: a powerful neurotoxic analogue of glutamate

John W. Olney, Vesela Rhee, Oi Lan Ho · Brain Research · 1974 · 705 citations

, , +14

1–5 of 819

Authors

3.4K

  1. CB
    Carlos Beas‐Zárate

    Universidad de Guadalajara, Mexico

    12 publications · 478 citations

    12

    h-index

  2. AA
    Akinori Akaike

    Kyoto University, Japan

    11 publications · 436 citations

    11

    h-index

  3. SS
    Shun Shimohama

    Kyoto University, Japan

    8 publications · 614 citations

    8

    h-index

  4. TK
    Toshiaki Kume

    Kyoto University, Japan

    8 publications · 248 citations

    8

    h-index

  5. DW
    Dennis W. Choi

    Washington University in St. Louis, United States

    7 publications · 9.6K citations

    7

    h-index

1–5 of 3.4K

Institutions

932

  1. Washington University in St. Louis

    St Louis, United States

    21 h-index

    75 publications

    9K citations

  2. Johns Hopkins University

    Baltimore, United States

    18 h-index

    43 publications

    8.6K citations

  3. Harvard University

    Cambridge, United States

    16 h-index

    57 publications

    3.5K citations

  4. Kyoto University

    Kyoto, Japan

    14 h-index

    97 publications

    5.5K citations

  5. National Institutes of Health

    Bethesda, United States

    13 h-index

    43 publications

    14.3K citations

  6. Universitat de Barcelona

    Barcelona, Spain

    12 h-index

    48 publications

    2.6K citations

  7. Universidad Nacional Autónoma de México

    Mexico City, Mexico

    12 h-index

    30 publications

    1.3K citations

  8. Universidad de Guadalajara

    Guadalajara, Mexico

    11 h-index

    42 publications

    1.5K citations

1–8 of 932

Venues

  1. Brain Research

    86 publications · 6.5K citations

    46

    h-index

  2. Neuroscience Letters

    59 publications · 3.7K citations

    31

    h-index

  3. Journal of Neuroscience

    30 publications · 4.8K citations

    30

    h-index

  4. Neuroscience

    31 publications · 2K citations

    25

    h-index

  5. Experimental Neurology

    27 publications · 1.6K citations

    24

    h-index

1–5