Autocrine stimulation of a human lung mesothelioma cell line is mediated through the transforming growth factor alpha/epidermal growth factor receptor mitogenic pathway

Autocrine Secretion and Malignant Transformation of Cells

Michael B. Sporn, George J. Todaro · New England Journal of Medicine · 1980 · 1.4K citations

Pathology, Cell Proliferation, Cell Growth +19

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.

Tomoyuki Kawamoto, Jun Sato, Anh D. Le et al. · Proceedings of the National Academy of Sciences · 1983 · 793 citations · Full text

Epidermal Growth Factor, Immunology, Cell Proliferation +16

Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung.

Valerie W. Rusch, José Baselga, Carlos Cordon‐Cardo et al. · PubMed · 1993 · 488 citations

Lung Inflammation, Pathology, Primary Nsclc +16

Transforming growth factor-alpha. A model for membrane-anchored growth factors.

Joan Massagué · Journal of Biological Chemistry · 1990 · 427 citations · Full text

Developmental Biology, Medicine, Membrane Transport +6

Transmembrane TGF-α precursors activate EGF/TGF-α receptors

Rainer K. Brachmann, Patricia B. Lindquist, Mariko Nagashima et al. · Cell · 1989 · 424 citations

Signal Transduction, Molecular Physiology, Receptor Tyrosine Kinase +6