Rainer K. Brachmann

Transmembrane TGF-α precursors activate EGF/TGF-α receptors

Rainer K. Brachmann, Patricia B. Lindquist, Mariko Nagashima et al. · Cell · 1989 · 425 citations

Life Sciences, Cell Biology, Molecular Biology +13

Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53

Ting Wang, Jue Zeng, Craig B. Lowe et al. · Proceedings of the National Academy of Sciences · 2007 · 405 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors

Antonio Jimeno, Michael A. Gordon, Rashmi Chugh et al. · Clinical Cancer Research · 2017 · 204 citations

Medicine, Oncology, Pharmacology +17

Phosphoinositide 3-Kinase (PI3K) Pathway Alterations Are Associated with Histologic Subtypes and Are Predictive of Sensitivity to PI3K Inhibitors in Lung Cancer Preclinical Models

Jill M. Spoerke, Carol O’Brien, Ling Huw et al. · Clinical Cancer Research · 2012 · 179 citations · Full text

Medicine, Cancer Biology, Oncology +17

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

Rainer K. Brachmann, Kexin Yu, Yolanda Eby et al. · The EMBO Journal · 1998 · 161 citations · Full text

Medicine, Genetics, Molecular Genetics +15