Effect of natsudaidain isolated from<i>Citrus</i>plants on TNF-α and cyclooxygenase-2 expression in RBL-2H3 cells

Abstract

These findings suggest that natsudaidain inhibits tumour necrosis factor-alpha and cyclooxygenase-2 production by suppressing p38 MAPK phosphorylation but not p65 NFkappaB phosphorylation, and that natsudaidain might alleviate inflammatory diseases.