Publication | Open Access

Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization

Medicinal ChemistryVirtual ScreeningBioorganic ChemistryHit IdentificationBiochemistryDrug TargetNatural SciencesNovel Ck1 InhibitorsMedicineRational Drug DesignCommon-feature Pharmacophore ModelDrug DevelopmentChemical BiologyPharmacologyDrug Discovery