Generation of high-affinity DNA aptamers using an expanded genetic alphabet

Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

Craig Tuerk, Larry Gold · Science · 1990 · 10.4K citations

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In vitro selection of RNA molecules that bind specific ligands

Andrew D. Ellington, Jack W. Szostak · Nature · 1990 · 9.7K citations

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Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

Larry Gold, Deborah Ayers, Jennifer Bertino et al. · PLoS ONE · 2010 · 1.7K citations · Full text

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2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF165)

Judy Ruckman, Louis S. Green, Jim Beeson et al. · Journal of Biological Chemistry · 1998 · 735 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +14

Synthetic Genetic Polymers Capable of Heredity and Evolution

Vitor B. Pinheiro, Alexander I. Taylor, Christopher Cozens et al. · Science · 2012 · 713 citations · Full text

Life Sciences, Genetics, Molecular Biology +17