Concepedia

QSAR model for human pregnane X receptor (PXR) binding: Screening of environmental chemicals and correlations with genotoxicity, endocrine disruption and teratogenicity

Marianne Dybdahl, Nikolai Georgiev Nikolov, Eva Bay Wedebye, Svava Ósk Jónsdóttir, Jay Russell Niemelä

Toxicology and Applied Pharmacology · 2012 · 35 citations · 24 references

DOI

Concepts

References

24

The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity

Ryan E. Watkins, G. Bruce Wisely, Linda B. Moore et al. · Science · 2001 · 755 citations

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Describing the validity of carcinogen screening tests

Jeremy Cooper, Rodolfo Saracci, Philip Cole · British Journal of Cancer · 1979 · 350 citations

, , +12

The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants

Jiong Zhang, Peter Kuehl, E D Green et al. · Pharmacogenetics · 2001 · 290 citations

, , +13

The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution

S. A. Jones · Molecular Endocrinology · 2000 · 259 citations

, , +16

LeadScope:  Software for Exploring Large Sets of Screening Data

Gulsevin Roberts, Glenn J. Myatt, Wayne P. Johnson et al. · Journal of Chemical Information and Computer Sciences · 2000 · 155 citations

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