Comparison of protein kinase C functional assays to clarify mechanisms of inhibitor action

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

Hiroyoshi Hidaka, Masaki Inagaki, Sachiyo Kawamoto et al. · Biochemistry · 1984 · 2.7K citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications · 1986 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +10

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

Yusuf A. Hannun, Carson R. Loomis, Alfred H. Merrill et al. · Journal of Biological Chemistry · 1986 · 1.2K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

Akira Kishimoto, N Kajikawa, Makoto Shiota et al. · Journal of Biological Chemistry · 1983 · 601 citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Inhibition of protein kinase C by tamoxifen.

C A O'Brian, Rob M. J. Liskamp, David H. Solomon et al. · PubMed · 1985 · 468 citations · Full text

Life Sciences, Pharmacology, Cell Signaling +10