C A O'Brian

Inhibition of protein kinase C by tamoxifen.

C A O'Brian, Rob M. J. Liskamp, David H. Solomon et al. · PubMed · 1985 · 468 citations

Molecular Pharmacology, Signal Transduction, Protein Kinase C +12

Elevated protein kinase C expression in human breast tumor biopsies relative to normal breast tissue.

C A O'Brian, V. G. Vogel, S. Eva Singletary et al. · PubMed · 1989 · 213 citations

Pkc Levels, Breast Oncology, Pathology +18

Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family.

Gerard M. Housey, C A O'Brian, Mark D. Johnson et al. · Proceedings of the National Academy of Sciences · 1987 · 153 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +17

Triphenylethylenes: A New Class of Protein Kinase C Inhibitors

C A O'Brian, Rob M. J. Liskamp, David H. Solomon et al. · JNCI Journal of the National Cancer Institute · 1986 · 136 citations

Medicinal Chemistry, Lipid Environment, Signal Transduction +14

Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue.

C A O'Brian, Gerard M. Housey, I. Bernard Weinstein · PubMed · 1988 · 79 citations

Chemoprevention Strategy, Pharmacotherapy, Chemical Biology +21