PAF increases vascular permeability in selected tissues: Effect of BN-52021 and L-655,240

Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin.

S M Prescott, Guy A. Zimmerman, Thomas M. McIntyre · Proceedings of the National Academy of Sciences · 1984 · 435 citations · Full text

Endothelial Cells, Immunology, Blood Cell +25

Increased biosynthesis of platelet-activating factor in activated human eosinophils.

T. Lee, Daniel J. Lenihan, Boyd Malone et al. · Journal of Biological Chemistry · 1984 · 420 citations · Full text

Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives

B. Boris Vargaftig, Jean Lefort, Michel Chignard et al. · European Journal of Pharmacology · 1980 · 415 citations

Inflammation, Asthma, Thrombopoiesis +11

Activation of human neutrophils with 1-<i>O</i>-hexadecyl/octadecyl-2-acetyl-<i>sn</i>-glycerol-3-phosphorylcholine (platelet activating factor).

James O. Shaw, R. Neal Pinckard, K S Ferrigni et al. · The Journal of Immunology · 1981 · 385 citations

Biosynthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) from 1-alkyl-2-acyl-sn-glycero-3-phosphocholine by rat alveolar macrophages. Phospholipase A2 and acetyltransferase activities during phagocytosis and ionophore stimulation.

Daniel H. Albert, Fred Snyder · Journal of Biological Chemistry · 1983 · 264 citations · Full text