Catalytic asymmetric prop-2-ynylation involving the use of the bifunctional synergetic reagent Et2BSPri

Abstract

Efficient catalytic asymmetric prop-2-ynylation of achiral aldehydes with allenyltributylstannane promoted by a BINOL–Ti IV complex (10 mol%) is achieved with high enantioselectivity by the use of Et 2 BSPr i .