The γ-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats

GABA in nervous system function

Leslie L. Iversen · Journal of the Neurological Sciences · 1977 · 1K citations

Life Sciences, Neurobiology, Neuroscience +12

Inhibitory, GABAergic Nerve Terminals Decrease at Sites of Focal Epilepsy

Charles E. Ribak, A. Basil Harris, James E. Vaughn et al. · Science · 1979 · 348 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY NIPECOTIC ACID, VARIOUS ISOXAZOLES AND RELATED COMPOUNDS

Povl Krogsgaard‐Larsen, Graham A.R. Johnston · Journal of Neurochemistry · 1975 · 328 citations

Life Sciences, Neuroscience, Pharmacology +12

Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

Erik B. Nielsen, Peter D. Suzdak, Knud Erik Andersen et al. · European Journal of Pharmacology · 1991 · 232 citations

Medicine, Medicinal Chemistry, Pharmacology +13

<i>(R)‐N</i>‐[4,4‐Bis(3‐Methyl‐2‐Thienyl)but‐3‐en‐1‐yl]Nipecotic Acid Binds with High Affinity to the Brain γ‐Aminobutyric Acid Uptake Carrier

Erik B. Nielsen, Ursula Sonnewald, Lars J. S. Knutsen et al. · Journal of Neurochemistry · 1990 · 228 citations

Life Sciences, Neuroscience, Pharmacology +5