Single-tube reaction using peptide nucleic acid as both PCR clamp and sensor probe for the detection of rare mutations

Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

Peter E. Nielsen, Rolf H. Berg, Ole Buchardt · Science · 1991 · 3.3K citations

Life Sciences, Biomolecular Engineering, Molecular Biology +17

DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells.

Sabine Jahr, Hannes Hentze, Susanne Englisch et al. · PubMed · 2001 · 2.2K citations

Life Sciences, Molecular Biology, Oncology +10

PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules

Ole Buchardt, Leif Christensen, Carsten Behrens et al. · Nature · 1993 · 2.1K citations

Life Sciences, Biology, Molecular Biology +11

3'-Minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures

Igor V. Kutyavin · Nucleic Acids Research · 2000 · 795 citations

Life Sciences, Genetics, Molecular Biology +13

Antisense and Antigene Properties of Peptide Nucleic Acids

Jeffery C. Hanvey, Nancy J. Peffer, John Bisi et al. · Science · 1992 · 536 citations

Life Sciences, Genetics, Molecular Biology +17