Short-term, daily exposure to cold temperature may be an efficient way to prevent muscle atrophy and bone loss in a microgravity environment

IFN-γ stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation

Yuhao Gao, Francesco Grassi, Michaela Robbie Ryan et al. · Journal of Clinical Investigation · 2006 · 454 citations · Full text

Medicine, Endocrinology, Immunology +17

Exercise in space: human skeletal muscle after 6 months aboard the International Space Station

Scott Trappe, D. L. Costill, Philip M. Gallagher et al. · Journal of Applied Physiology · 2009 · 447 citations

Education, Kinesiology, Physiology +17

Prolonged space flight-induced alterations in the structure and function of human skeletal muscle fibres

R. H. Fitts, Scott Trappe, D. L. Costill et al. · The Journal of Physiology · 2010 · 359 citations · Full text

Life Sciences, Anatomy, Physiology +17

Effect of a 17 day spaceflight on contractile properties of human soleus muscle fibres

Jeffrey J. Widrick, S. T. Knuth, K. M. Norenberg et al. · The Journal of Physiology · 1999 · 269 citations · Full text

Life Sciences, Biophysics, Physiology +17

Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission

Dorianna Sandonà, Jean‐François Desaphy, Giulia Maria Camerino et al. · PLoS ONE · 2012 · 187 citations · Full text

Life Sciences, Biochemistry, Physiology +16