Assessment of Population Structure and Major Circulating Phylogeographical Clades of <i>Mycobacterium tuberculosis</i> Complex in Bangladesh Suggests a High Prevalence of a Specific Subclade of Ancient <i>M. tuberculosis</i> Genotypes

Abstract

Spoligotyping was performed to study the population structure of Mycobacterium tuberculosis complex strains (n = 224) from Bangladesh. Strains were split into principal genetic group 1 (PGG 1 [75.0%]) and PGG 2 and 3 (25%). Forty-nine strains with a new spoligotype signature and considered as south or southeast Asian-linked emerging clones were designated as "Matlab type."