Lacosamide neurotoxicity associated with concomitant use of sodium channel-blocking antiepileptic drugs: A pharmacodynamic interaction?

Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies

Philip N. Patsalos, David J. Berry, Blaise F. D. Bourgeois et al. · Epilepsia · 2008 · 1.1K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Efficacy and Safety of Oral Lacosamide as Adjunctive Therapy in Adults with Partial‐Onset Seizures

Elinor Ben‐Menachem, Victor Biton, Dalius Jatužis et al. · Epilepsia · 2007 · 483 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +9

The Investigational Anticonvulsant Lacosamide Selectively Enhances Slow Inactivation of Voltage-Gated Sodium Channels

Adam C. Errington, Thomas Stöhr, Cara Heers et al. · Molecular Pharmacology · 2007 · 434 citations

Life Sciences, Neuroscience, Pharmacology +17

Adjunctive lacosamide for partial‐onset seizures: Efficacy and safety results from a randomized controlled trial

Péter Halász, Reetta Kälviäinen, Maria Mazurkiewicz‐Bełdzińska et al. · Epilepsia · 2009 · 392 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +11

Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin

Sarah K. Tate, Chantal Depondt, Sanjay M. Sisodiya et al. · Proceedings of the National Academy of Sciences · 2005 · 347 citations

Medicine, Pharmacology, Pharmacotherapy +14