Nickel-Catalyzed Highly Regio- and Chemoselective Cocyclotrimerization of Propiolates with Allenes: A Novel Route to Polysubstituted Benzene Derivatives

Abstract

The Ni(dppe)Br(2)/Zn system effectively catalyzes the cocyclotrimerization of propiolates with allenes. The reaction is highly regio- and chemoselective to afford polysubstituted benzene derivatives in good to excellent yields. [reaction: see text]