Australian and New Zealand Journal of Surgery · 1989 · 15 citations · 24 references
MedicineInternal MedicineSurgeryEmergency SurgeryGeneral SurgeryPerioperative SafetyGastrointestinal PerforationUlcer ManagementGastric Ulcer ManagementGastrointestinal Perforation ManagementMortality Rate AssessmentPerforated UlcerSurgical Decision-makingSurgical Decision-making CriteriaSurgical Outcome Assessment
Between 1966 and 1987, 116 patients with 119 episodes of perforation were admitted to Box Hill Hospital into one surgical unit, and 91 patients with 92 episodes were admitted into the other, with patients being admitted in alternate weeks. In the former unit, in order to avoid surgery in those patients whose ulcers had sealed spontaneously, a deliberative approach was followed according to a strict protocol--involving a deliberate time delay in surgical decision-making. In the latter unit, a more conventional approach was adopted, and patients in that unit are used as a retrospective comparison. In the first unit, of 115 episodes which followed the protocol, six were unresuscitable, 15 needed immediate surgery and 94 followed a delayed approach. Of that 94, 12 needed surgery at 4-6 h, and a further eight needed later surgery. Seventy-four (68% of 'operable' patients) did not require corrective surgery at all, for their episode of perforation. The operable mortality rate was lower (6% compared with 13%), the bedstay was shorter, the prolonged bedstay rate was lower, and the morbidity was no worse, than those patients treated more conventionally in the second unit.
24
Guest Lecture: The Non-Surgical Treatment of Perforated Peptic Ulcer
H. Wayne Taylor · Gastroenterology · 1957 · 95 citations
Medicine, Clinical Sciences, Surgery +13
PERFORATED PEPTIC ULCER TREATED WITHOUT OPERATION
H. Wayne Taylor · The Lancet · 1946 · 90 citations
John Boey, John Wong · World Journal of Surgery · 1987 · 86 citations
Medicine, Surgery, General Surgery +16
What has happened to perforated peptic ulcer?
R M Watkins, Ashley R. Dennison, J Collin · British journal of surgery · 1984 · 79 citations
Selective Treatment of Duodenal Ulcer with Perforation
Arthur J. Donovan, Thomas L. Vinson, Gilbert O. Maulsby et al. · Annals of Surgery · 1979 · 75 citations
Medicine, Surgery, Emergency Surgery +12