γ-Ray and hydrogen peroxide induction of gene amplification in hamster cells deficient in DNA double strand break repair

Production of large amounts of hydrogen peroxide by human tumor cells.

Ted P. Szatrowski, Carl Nathan · PubMed · 1991 · 2.5K citations

Life Sciences, Biochemistry, Oncology +17

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

T Blunt, Nicholas Finnie, Guillermo E. Taccioli et al. · Cell · 1995 · 865 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Classification and relationships of induced chromosomal structual changes.

John R. K. Savage · Journal of Medical Genetics · 1976 · 456 citations · Full text

Life Sciences, Cell Biology, Genetics +17

Phagocytes as Carcinogens: Malignant Transformation Produced by Human Neutrophils

Sigmund A. Weitzman, Alan B. Weitberg, Edward P. Clark et al. · Science · 1985 · 444 citations

Life Sciences, Immunology, Oncology +17

Expression of Fragile Sites Triggers Intrachromosomal Mammalian Gene Amplification and Sets Boundaries to Early Amplicons

Arnaud Coquelle, Eva Pipiras, Franck Toledo et al. · Cell · 1997 · 395 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12