Hyaluronan enhances cartilage repair through low grade tissue remodeling involving cytokines and matrix metalloproteinases

Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.

John L. Fowlkes, Jan J. Enghild, Ko Suzuki et al. · Journal of Biological Chemistry · 1994 · 348 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants

Frank P. Luyten, Vincent Hascall, S. Peter Nissley et al. · Archives of Biochemistry and Biophysics · 1988 · 311 citations

Engineering, Biochemistry, Cell Biology +16

Viscosupplementation with Hylan G-F 20: A 26-week controlled trial of efficacy and safety in the osteoarthritic knee

Manfred Wobig, Adalbert Dickhut, Raimund Maier et al. · Clinical Therapeutics · 1998 · 295 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +7

Nitric Oxide Mediates Interleukin-1-Induced Gene Expression of Matrix Metalloproteinases and Basic Fibroblast Growth Factor in Cultured Rabbit Articular Chondrocytes

Kazuhiro Sasaki, Tetsuo Hattori, Tomotsumi Fujisawa et al. · The Journal of Biochemistry · 1998 · 271 citations

Life Sciences, Cell Biology, Pathology +15

Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan®) in osteoarthritis of the knee

V. Listrat, X Ayral, Francesca Patarnello et al. · Osteoarthritis and Cartilage · 1997 · 253 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +12