Concepedia

A Multipotent Progenitor Domain Guides Pancreatic Organogenesis

Qiao Zhou, Anica C. Law, Jayaraj Rajagopal, W. J. Anderson, Paul A. Gray, Douglas A. Melton

Developmental Cell · 2007 · 540 citations · 39 references

DOIFull text

Open access

Concepts

References

39

Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

Yuval Dor, Juliana Brown, Olga I. Martinez et al. · Nature · 2004 · 2.2K citations

, , +14

Insulin-promoter-factor 1 is required for pancreas development in mice

Jörgen Jönsson, Lena Carlsson, Helena Edlund · Nature · 1994 · 1.8K citations

, , +13

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Martin F. Offield, Tom L. Jetton, Patricia A. Labosky et al. · Development · 1996 · 1.5K citations

, , +16

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Guoqiang Gu, Jolanta Dubauskaite, Douglas A. Melton · Development · 2002 · 1.5K citations

, , +16

<i>neurogenin3</i> is required for the development of the four endocrine cell lineages of the pancreas

Gérard Gradwohl, Andrée Dierich, Marianne LeMeur et al. · Proceedings of the National Academy of Sciences · 2000 · 1.5K citations

, , +17