Concepedia

Germ-line transmission of a disrupted β2microglobulin gene produced by homologous recombination in embryonic stem cells

Maarten Zijlstra, En Li, F Sajjadi, Suresh Subramani, Rudolf Jaenisch

Nature · 1989 · 353 citations · 22 references

DOI

Concepts

References

22

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

, , +12

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

R. Lindsay Williams, Douglas J. Hilton, Shirley Pease et al. · Nature · 1988 · 2K citations

, , +15

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

, , +15

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

Allan Bradley, Martin Evans, M. H. Kaufman et al. · Nature · 1984 · 1.5K citations

, , +10

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

Elizabeth J. Robertson, Allan Bradley, Michael R. Kuehn et al. · Nature · 1986 · 756 citations

, , +14