Concepedia

Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists

Alan S. Florjancic, Sridhar Peddi, Arturo Perez‐Medrano, Biqin Li, Marian T. Namovic, George Grayson, Diana L. Donnelly‐Roberts, Michael F. Jarvis, William A. Carroll

Bioorganic & Medicinal Chemistry Letters · 2008 · 32 citations · 10 references

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References

10

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

Iain P. Chessell, Jonathan P. Hatcher, C. Bountra et al. · Pain · 2005 · 784 citations

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Tissue distribution of the P2X7 receptor

Ginetta Collo, S. Neidhart, Eric Kawashima et al. · Neuropharmacology · 1997 · 498 citations

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Absence of the P2X7 Receptor Alters Leukocyte Function and Attenuates an Inflammatory Response

Jeffrey M. Labasi, Nina Petrushova, Carol Donovan et al. · The Journal of Immunology · 2002 · 487 citations · Full text

, , +17

A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat

Prisca Honoré, Diana L. Donnelly‐Roberts, Marian T. Namovic et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 409 citations

, , +17

Reanalysis of P2X<sub>7</sub>Receptor Expression in Rodent Brain

Joan A. Sim, Mark T. Young, Hye-Youn Sung et al. · Journal of Neuroscience · 2004 · 262 citations · Full text

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