Concepedia

A novel synthesis of β-lactam fused cyclic enediynes by intramolecular Kinugasa reaction

Chemical Communications · 2006 · 34 citations · 23 references

Abstract

A general synthetic route to beta-lactam-fused enediynes by intramolecular Kinugasa reaction has been successfully developed. The method has widened the scope of Kinugasa reaction in the synthesis of sensitive systems like the one described in this communication.

References

23

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

Chemical Engineering, Catalytic Substitutions, Engineering +8

A Convenient Synthesis of Ethynylarenes and Diethynylarenes

S. Takahashi, Y. Kuroyama, Kenkichi Sonogashira et al. · Synthesis · 1980 · 1.1K citations

Alkene Metathesis, Organic Chemistry, Convenient Synthesis +3

Reactive 1,4-dehydroaromatics

Robert G. Bergman · Accounts of Chemical Research · 1973 · 751 citations

Altmetrics, Donut Icon, Information +9

Cyclic conjugated enediynes related to calicheamicins and esperamicins: calculations, synthesis, and properties

K.C. Nicolaou, Yuki Ogawa, Guido Zuccarello et al. · Journal of the American Chemical Society · 1988 · 286 citations

Pharmaceutical Science, Bioorganic Chemistry, Engineering +11

Copper-Catalyzed Reaction of Terminal Alkynes with Nitrones. Selective Synthesis of 1-Aza-1-buten-3-yne and 2-Azetidinone Derivatives

Masahiro Miura, Masahiro Enna, Kazumi Okuro et al. · The Journal of Organic Chemistry · 1995 · 283 citations

Terminal Alkynes, 2-Azetidinone Derivatives, Engineering +13