Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS

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Christopher Baines, Robert A. Kaiser, Nicole H. Purcell et al. · Nature · 2005 · 2.2K citations

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Reactive Oxygen Species (Ros-Induced) Ros Release

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Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

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Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.

M Crompton, H Ellinger, A Costi · PubMed · 1988 · 848 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

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