Insulin-like Growth Factor-I Signaling Mechanisms, Type I Collagen and Alpha Smooth Muscle Actin in Human Fetal Lung Fibroblasts

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.3K citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS

WilliamR. Roche, J H Williams, Richard Beasley et al. · The Lancet · 1989 · 1.1K citations

Medicine, Clinical Sciences, Pathology +10

Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-κB

Lee V. Madrid, Cun-Yu Wang, Denis C. Guttridge et al. · Molecular and Cellular Biology · 2000 · 626 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Stimulation of Collagen Formation by Insulin and Insulin-Like Growth Factor I in Cultures of Human Lung Fibroblasts*

Ronald H. Goldstein, Christine F. Poliks, Paul F. Pilch et al. · Endocrinology · 1989 · 230 citations

Life Sciences, Endocrinology, Cell Proliferation +12