Genetic Evidence Linking SAP, the X-Linked Lymphoproliferative Gene Product, to Src-Related Kinase FynT in TH2 Cytokine Regulation

Generation and Analysis of Interleukin-4 Deficient Mice

Ralf Kühn, Klaus Rajewsky, Werner Müller · Science · 1991 · 1.3K citations

Life Sciences, Hematology, Immunology +17

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

Manfred Köpf, Graham Le Gros, Martin F. Bachmann et al. · Nature · 1993 · 1.2K citations

Life Sciences, Immunology, Molecular Genetics +10

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

Joan Sayós, Chengbin Wu, M. Morra et al. · Nature · 1998 · 942 citations

Life Sciences, Immunology, Molecular Biology +10

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

Paula Stein, Susan Solliday Rich, Philippe Soriano · Cell · 1992 · 569 citations

Life Sciences, Cell Biology, Immunology +12

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

Mark W. Appleby, Jane A. Gross, M. Cooke et al. · Cell · 1992 · 510 citations

Life Sciences, Genetics, Immunology +12