Tc-99m MDP Scanning in a Patient With Extensive Fibrodysplasia Ossificans Progressiva

Abstract

Fibrodysplasia ossificans progressive (FOP) is an extremely rare disorder characterized by unremitting heterotopic ossification associated with typical skeletal abnormalities. Although most cases arise sporadically, it is inherited as an autosomal dominant condition. It is not necessary for heterotropic ossification to begin with trauma as in myositis ossificans, so unusual sites of involvement may show various patterns of scintigraphic findings in patients with FOP. The authors report a case of extensive FOP with an interesting Tc-99m MDP bone scan.