Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

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Prevalence of Age-related Maculopathy

Ronald Klein, Kathryn L.P. Linton · Ophthalmology · 1992 · 1.8K citations

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Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization.

Adriano Henney, Philip R. Wakeley, Michael J. Davies et al. · Proceedings of the National Academy of Sciences · 1991 · 593 citations · Full text

Medicine, Cardiology, Molecular Biology +15

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.

Kevin J. Leco, Rama Khokha, Nadine Pavloff et al. · Journal of Biological Chemistry · 1994 · 481 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14