Concepedia

Resistance to Apoptosis and Up Regulation of Bcl-2 In Benign Prostatic Hyperplasia After Androgen Deprivation

Marina Cardillo, Guy Berchem, Mary Anne Tarkington, Stanisław Krajewski, Maryla Krajewski, John C. Reed, Timothy J. Tehan, Louis G. Ortega, Janice M. Lage, Edward P. Gelmann

The Journal of Urology · 1997 · 54 citations · 39 references

DOI

Abstract

BPH demonstrated increased staining for Bcl-2 after androgen deprivation that may render hyperplastic epithelium relatively resistant to apoptosis induced acutely by androgen withdrawal.

References

39

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

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Studies on Prostatic Cancer: I. The Effect of Castration, of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate

Charles Huggins, Clarence V. Hodges · The Journal of Urology · 2002 · 3.2K citations

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Lawrence Boise, Maribel González‐García, C E Postema et al. · Cell · 1993 · 3.1K citations · Full text

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The Development of Human Benign Prostatic Hyperplasia with Age

Stephen J. Berry, Donald S. Coffey, Patrick C. Walsh et al. · The Journal of Urology · 1984 · 2.5K citations

STUDIES ON PROSTATIC CANCER

Charles Huggins · Archives of surgery · 1941 · 1.5K citations

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